Ocular Surface Disorder

Dry Eye refers to a group of disorders caused by damage to the corneal epithelium, the outermost layer of the cornea. It acts as a barrier to protect the cornea, preventing evaporation of fluids from tears and keeping bacteria from entering the epithelium and corneal stroma.

This disorder is characterized by pain, redness and poor vision, potentially leading to permanent corneal or conjunctival injury in the long run. Several conditions, such as dry eye disease, are associated with this disorder. When treating ocular surface disorder, the goal is to enhance the healing process and achieve symptom relief.



Kerato-conjunctivitis sicca, or dry eye syndrome (DES), is a common yet treatable eye condition in which the eyes are not sufficiently or properly lubricated [2]. This leads to a host of uncomfortable symptoms such as eye redness a stinging or burning sensation in the eyes, stringy mucus in or around the eyes, blurred vision, excessive tearing, and a gritty feeling, similar to having something in your eyes.The severity of DES symptoms can range from mildly bothersome to incapacitating.

Symptoms can develop as a result of dysfunctional tear syndrome, lacrimal keratoconjunctivitis, evaporative tear deficiency/evaporative dry eye disease (EDED), meibomian gland dysfunction (MGD), and LASIK-induced neurotrophic epitheliopathy (LINE), among others causes.

Repairing the tear film should be the main focus when treating dry eye.


corneal damage

Certain eye conditions require surgical intervention. However, ocular surgery, such as refractive surgery (LASIK), cataract surgery, glaucoma surgery, and corneal transplant, can induce or exacerbate dry eye following the operation.

In the case of refractive surgery, the surgical removal of corneal tissue causes nerve loss from the corneal stroma. This reduces corneal sensitivity and provokes a decrease in tearing and blinking. The purpose of tears is to wash out irritants that may have come into contact with the eye, whereas blinking attempts to spread the tear fluid over the ocular surface. Decreased tearing and blinking causes the tears to evaporate more easily, causing typical symptoms of dry eye disease.

As a result, dry eye-associated symptoms are extremely frequent in patients having undergone ocular surface surgery. Dry eye may also hinder corneal healing and decrease the optical quality of the cornea. It is thus important to take the necessary steps to identify dryness and use effective treatment



While there are many treatment options available for dry eye disease, both prescription and over the counter, eye drops and devices, these solutions do not work for everyone. When dry eye is particularly stubborn or severe, a more advanced solution may be needed.

Lipitear™ Multi is a clinically-proven formula that imitates and repairs the natural tear film. It forms an elastic shield that restores the right environment for a healthy ocular surface, thus facilitating the healing process of the epithelium and rebuilding a uniform and smooth ocular surface for clear and comfortable vision. Its unique formulation also helps reduce the typical signs and symptoms in patients suffering from dry eye, controlling tear evaporation by properly lubricating the ocular surface, thus moistening the ocular surface.



Natural and Easy to use

• Preservative-free microemulsion based eye drops
• All-natural ingredients (vegan phospholipids and medium-chain triglycerides)
• Clinically proven to mimic the natural tear film

Protects and Heals

• Forms an elastic lipid shield that controls the evaporation of tear film and restores the proper microenvironment for a healthy ocular surface
•  Currently the only available eye drop that is clinically proven to support and enhance corneal re-epithelization following mechanical, traumatic and post surgical corneal epithelial damage
• Enhances re-epithelization by restoring a physiological microenvironment and modulating cholesterol metabolism
• Reduces micro traumas caused by blinking
• Efficiently restores a uniform and smooth ocular surface
• Thanks to its unique composition, Lipitear™ Multi is more effective in reducing signs and symptoms of dry eye than other eye drops containing hyaluronic acid..



Efficacy and safety in reducing signs and symptoms in patients suffering from dry-eye

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Effect of LIPITEARTM (formerly LIPIMIXTM) on the healing of corneal epithelium following mechanical erosion

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First promising clinical results with Lipitear™ for neurotrophic keratitis treatment.

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Effect on the re-epithelization process in patients who underwent PRK

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